4% cirbadeynta Gentamyclin sulfate
.png)
.png)
.png)
.png)
Tilmaan
Muuqashada:Alaabtani waa mid aan midab lahayn ama dareere cad oo cagaar ah oo hurdi ah ama hurdi ah.
Falka dawooyinka:PharmacodynamicGentamycinwaa antibiyootig aminoglycoside ah oo leh saameyn bakteeriyada bakteeriyada kala duwan (sida Escherichia coli, Klebsiella, Proteus, Pseudomonas aeruginosa, Pasteurella, Salmonella, iwm.) iyo Staphylococcus aureus (oo ay ku jiraan β-lactamase soo saarista noocyada).Inta badan cocci (Streptococcus pyogenes, pneumococcus, Streptococcus faecalis, iwm.), bakteeriyada anaerobic (Bacteroides ama Clostridium), qaaxada Mycobacterium, Rickettsia iyo fangaska ayaa u adkaysata alaabtan.
Farmashiyaha:Nuugista ayaa degdeg ah oo dhammaystiran ka dib cirbadeynta muruqyada.Heerarka ugu sarreeya waxaa lagu gaaraa 0.5 ilaa 1 saac gudahood.Helitaanka bioavailability ayaa ka badan 90% cirbadeynta muruqa hoose ama gudaha.Waxaa inta badan lagu soo saaraa sifaynta glomerular waxayna ka dhigan tahay 40% ilaa 80% qiyaasta la maamulo.Ciribtirka nolosha nuska ka dib cirbadeynta murqaha waa 1.8 ilaa 3.3 saacadood fardaha, 2.2 ilaa 2.7 saacadood ee weylaha, 0.5 ilaa 1.5 saacadood eeyada iyo bisadaha, 1 saac ee lo'da iyo doofaarka, 1 ilaa 2 saacadood bakaylaha, iyo 2.3 ilaa 3.2 saacadaha idaha, dibi, lo'da, iyo riyaha caanaha.
Isdhexgalka daroogada:
(1) Isku darka Gentamycin iyo tetracycline iyo erythromycin waxay yeelan karaan saameyn liddi ku ah.
(2) Marka lagu daro cephalosporins, dextran, diuretics awood leh (sida furosemide, iwm.), iyo erythromycin, ototoxicity ee alaabtan waa la wanaajin karaa.
(3) Nasiyeyaasha murqaha lafaha (sida succinylcholine chloride, iwm.) ama daawooyinka saameyntan leh waxay kor u qaadi karaan saameynta xannibaadda neuromuscular ee HUMIRA.
Ficil iyo isticmaal
Antibiyootikada Aminoglycoside.Caabuqyada bakteeriyada Gram-negative iyo togan.
Qiyaasta iyo maamulka
(1) Ototoxicity.Waxay inta badan keentaa dhaawaca vestibular ee dhegta, taas oo ay uga sii dari karto ururinta daawooyinka si joogto ah loo maamulo ee hab ku xiran qiyaasta.
(2) Dareen-celin xasaasiyadeed oo marmar ah.Bisadaha ayaa aad u nugul, joogta ah waxay keeni kartaa lallabbo, matag, candhuuf iyo ataxia.
(3) Qiyaaso sare waxay sababi karaan xannibaado neuromuscular ah.Dhimashada shilalka badanaa waxay dhacdaa ka dib suuxinta guud ee hababka qalliinka ee eeyaha iyo bisadaha, oo lagu daro penicillin si looga hortago caabuqa.
(4) Waxa laga yaabaa inay keento nephrotoxicity la beddeli karo.
Ka taxadaritaan
(1) Gentamycin waxaa lagu dari karaa antibiyootiga β-lactam si loo daaweeyo caabuqyada daran, laakiin ma socon karto marka la isku daro vitro.
(2) Marka lagu daro penicillin, alaabtani waxay leedahay saameyn isku dhafan oo ku saabsan streptococci.
(3) Waxay leedahay niyad-jab xagga neef-mareenka ah mana aha in xididka la iska duro.
(4) Antagonism waxaa laga yaabaa inay ku dhacdo marka lagu daro tetracycline iyo erythromycin.
(5) Isku darka cephalosporins waxay kor u qaadi kartaa nephrotoxicity.
Muddada ka bixida
Doofaarka, lo'da iyo idaha 40 maalmood.
Kaydinta
Shaabadeeyey oo lagu kaydiyey meel mugdi ah oo qabow.
Hebei Veyong Pharmaceutical Co., Ltd, waxaa la aasaasay 2002, oo ku yaala Shijiazhuang City, Gobolka Hebei, Shiinaha, ee ku xiga caasimadda Beijing.Iyadu waa shirkad weyn oo GMP-shahaad ka siisay dawada xoolaha, oo leh R&D, wax soo saarka iyo iibinta API-yada caafimaadka xoolaha, diyaarinta, quudinta premixed iyo quudinta lagu daro.Iyada oo ah Xarunta Farsamada Gobolka, Veyong waxay dejisay nidaam R&D cusub oo loogu talagalay daawaynta cusub ee caafimaadka xoolaha, waana tan qaran ahaan loo yaqaan hal-abuurnimada tignoolajiyada ganacsiga xoolaha, waxaa jira 65 xirfadlayaal farsamo.Veyong waxa uu leeyahay laba saldhig wax soo saarka: Shijiazhuang iyo Ordos, kuwaas oo saldhigga Shijiazhuang daboolayaa meel of 78,706 m2, oo leh 13 alaabta API oo ay ku jiraan Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, iyo 11 khadadka wax soo saarka diyaarinta oo ay ku jiraan duritaanka, xal afka, , premix, bolus, sunta cayayaanka iyo jeermiska dila, iwm.Veyong waxay bixisaa API-yo, in ka badan 100-u-diyaarin summada leh, iyo adeegga OEM & ODM.
Veyong waxa ay muhiimad weyn siisaa maaraynta nidaamka EHS(Deegaanka, Caafimaadka & Badbaadada), waxa uuna helay shahaadooyinka ISO14001 iyo OHSAS18001.Veyong waxa lagu taxay istaraatiijiyada ganacsi ee soo koraya ee warshadaha ee Gobolka Hebei waxana ay xaqiijin kartaa sahayda joogtada ah ee alaabta.
Veyong wuxuu aasaasay nidaamka maaraynta tayada dhamaystiran, wuxuu helay shahaadada ISO9001, shahaadada Shiinaha GMP, shahaadada Australia APVMA GMP, shahaadada Itoobiya GMP, shahaadada Ivermectin CEP, waxayna dhaaftay baadhista US FDA.Veyong waxay leedahay koox xirfadlayaal ah oo diiwaan gelinta, iibinta iyo adeegga farsamada, shirkadeena waxay ka heshay ku tiirsanaanta iyo taageerada macaamiisheeda tiro badan oo tayo sare leh oo tayo sare leh, iibka hore iyo adeegga iibka ka dib, maamulka culus iyo sayniska.Veyong waxa ay wada shaqayn muddo dheer ah la samaysay shirkado badan oo caalami ah oo loo yaqaan farmashiyaha xoolaha oo wata badeecadaha loo dhoofiyo Yurub, Koonfurta Ameerika, Bariga Dhexe, Afrika, Aasiya, iwm in ka badan 60 waddan iyo gobollo.
